Academic Organization


http://www.med.niigata-u.ac.jp/ped/welcome.html




- Establishment and characterization of type IV collagen deficient mice.
- Pathogenesis of life-style related diseases in children, and establishment of its prevention and management.
- Effects of thyroid hormone deficiency on various organs and tissues in congenitally hypothyroid neonates.
- Establishment of the support and prevention system for child abuse.
- Clinical study on the plethysmogram in children.
- Pathogenesis of primary immunodeficiency diseases and allergic diseases.
- Development of new therapeutic approaches in IgA nephropathy.
- Analysis of the structure and the function of alpha3(IV), alpha4(IV), and alpha5(IV) collagen chains.
- Role of erythrocyte sodium-lithium counter-transport in the regulation of blood pressure in neonates.
- Studies on role of inflammatory cells in progressive renal disease.
- Molecular mechanism of macrophage mediated renal injury.
- Electrophysiological study on arrhythmia in children.
- Immuno-gene therapy for B-lineage malignancies.
- Genetic modification of primary human natural killer cells for cancer therapy.
- A novel strategy for treatment of acute lymphoblastic leukemia using gd T cells transduced with anti-CD19 chimeric receptor gene.




Makoto UCHIYAMAProfessorDepartment of Pediatrics
Atsushi TANAKAProfessorDepartment of Pediatrics
Takehiro KOBAYASHIAssociate professorDepartment of Pediatrics
Toru KIKUCHILecturerDepartment of Pediatrics
Masaki WADALecturerDepartment of Pediatrics
Yohei IKEZUMILecturerDepartment of Pediatrics
Hiroshi SUZUKIAssistantDepartment of Pediatrics
Chihaya IMAIAssistantDepartment of Pediatrics
Toshiaki SUZUKIAssistantDepartment of Pediatrics
Satoshi HASEGAWAAssistantDepartment of Pediatrics
Tohei USUDAAssistantDepartment of Pediatrics
Keisuke NAGASAKIAssistantDepartment of Pediatrics
Masaru IMAMURAAssistantDepartment of Pediatrics
Tamaki KARASAWAAssistantDepartment of Pediatrics
Utako KANEKOMedical staffDepartment of Pediatrics
Haruko IWABUCHIMedical staffDepartment of Pediatrics
Sakiko YOSHIDAMedical staff
Hisanori HaniuMedical staffDepartment of Pediatrics
Hiroya HASEGAWAMedical staffDepartment of Pediatrics
Tukasa TorigoeMedical staffDepartment of Pediatrics
Takayuki KANEKOMedical staffDepartment of Pediatrics
Ryosuke HOSOGAIMedical staffDepartment of Pediatrics
Akira KobayashiMedical staffDepartment of Pediatrics
Keisuke SHOJIMedical staffDepartment of Pediatrics





Ikezumi Y, Nikolic-Paterson DJ / Monocytes and Macrophages / Lai KN / Recent advances in IgA nephropathy / / World Scientific Publishing / Singapore / 2009 / 267 / 287 /



Takeuchi K, Yamamoto K, Kataoka S, Kakihara T, Tanaka A, Sato S, Uchiyama M. / High incidence of angiotensin I converting enzyme genotype II in Kawasaki disease patients with coronary aneurysm. / Eur J Pediatr / 156 / 266 / 268 / 1997 /

Toyabe S, Iiai T, Fukuda M, Kawamura T, Suzuki S, Uchiyama M, Abo T. / Identification of nicotinic acetylcholine receptors on lymphocytes in the periphery as well as thymus in mice. / Immunology / 92 / 201 / 205 / 1997 /

Toyabe S, Kuwano Y, Takeda K, Uchiyama M, Abo T. / IgA nephropathy -specific expression of the IgA Fc receptors (CD89) on blood phagocytic cells. / Clin Exp Immunol / 110 / 226 / 232 / 1997 /

Toyabe S, Seki S, Iiai T, Takeda K, Shirai K, Watanabe H, Hiraide H, Uchiyama M, Abo T. / Requirement of IL-4 and liver NK1+cells for concanavalin A-induced hepatic injury in mice. / J Immunol / 159 / 1537 / 1542 / 1997 /

Kawamura T, Toyabe S, Moroda T, Iiai T, Takahashi-Iwanaga H, Fukuda M, Watanabe H, Sekikawa H, Seki S, Abo T. / Neonatal granulocytosis is a postpartum event which is seen in the liver as well as inth blood. / Hepatology / 26 / 1567 / 1573 / 1997 /

Suzuki S, Toyabe S, Moroda T, Tada T, Tsukahara A, Iiai T, Minagawa M, Maruyama S, Hatakeyama K, Abo T. / Circadian rhythm of leukocytes and lymphocytes subsets and its possible correlation with the function of autonomic nervous system. / Clin Exp Immunol / 110 / 500 / 508 / 1997 /

Yamamura S, Toyabe S, Arai K, Kawamura T, Hanyu T, Takahashi H, Abo T. / Suppressive effect of rebamipide, a novel anti-ulcer agent, on the number and function of granulocytes and extrathymic T cells in mice. / Biomed Res / 18 / 103 / 112 / 1997 /

Kakihara T, Fukuda T, Kamishima T, Naito M, Tanaka A, Uchiyama M. / Resistance to Apoptosis Induced by Serum Depletion and All-Trans Retinoic Acid in Drug-Resistant Leukemic Cell Lines. / Leukemia Lymphoma / 26 / 369 / 376 / 1997 /

Yamamoto K, Kataoka S, Hashimoto N, Kakihara T, Tanaka A, Kawasaki T, Kikuchi T, Takahashi H, Uchiyama M. / Serum level and gene polymorphism of angiotensin I converting enzyme in Japanese children. / Acta Paediatr Jap / 39 / 1 / 5 / 1997 /

Kakihara T, Fukuda T, Yamada T, Tanaka A, Uchiyama M, Naito M, Emura I. / High reactivity of monoclonal antibody (TO73) with human malignant tumor cell line. / Pathol Int / 47 / 608 / 613 / 1997 /

Yamada T, Wakabayashi K, Kakihara T, Gejyo F, Takahashi H, Itoh Y. / Further characterization of a monoclonla antibody recognizing apolipoprotein E peptides in amyloid deposits. / Ann Clin Lab Sci / 27 / 276 / 281 / 1997 /

Fukuda T, Kamishima T, Kakihara T, Yamada T, Matsumoto K, Uchiyama M, Suzuki T. / Reactivity of antibody YU-311 in formalin-fixed, paraffin-embedded specimens of normal organs, non-hematopoietic tumors, and mast cell tumors. / Pathol Int / 47 / 512 / 517 / 1997 /

Watanabe A, Kakihara T, Yamamoto K, Kataoka S, Okada R, Tanaka A, Uchiyama M. / High-dose dexamethasone therapy for a 14-month-old boy with refractory idiopathic thrombocytopenic purpura. / Paediatr Jap / 39 / 368 / 370 / 1997 /

Kawasaki T, Hashimoto N, Kikuchi T, Takahashi H, Uchiyama M. / The relationship between fatty liver and hyperinsulinemia in obese Japanese children. / J Pediatr Gastr Nutr / 24 / 317 / 321 / 1997 /

Okubo S, Ichikawa I. / Role of angiotensin - insight from gene targeting studies. / Kidney Int / Suppl 63 / S 7 / S 9 / 1997 /

Chen X, Li W, Yoshida H, Tsuchida S, Nishimura H, Takamoto F, Okubo S, Fogo A, Matsusaka T, Ichikawa I. / Targeting deletion of angiotensin type 1B receptor gene in the mouse. / Am J Physiol / 272 / F299 / 304 / 1997 /

Okubo S, Niimura F, Nishimura H, Takemoto F, Fogo A, Matsusaka T, Ichikawa I. / Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion. / J Clin Invest / 99 / 855 / 60 / 1997 /

Niimura F, Okubo S, Fogo A, ichikawa I. / Temporal and spatial expression pattern of the angiotensinogen gene in mice and rats. / Am J Physiol / 272 / R142 / 7 / 1997 /

Naganuma Y, Konishi T, Hongou K, Tohyama J, Uchiyama M. / Epileptic seizures and event-related potentials (P300) in childhood partial epilepsies. / Clin Electroencephal / 28 / 106 / 111 / 1997 /

Fujinaka H, Yamamoto T, Feng L, Kawasaki K, Yaoita E, Hirose S, Goto S, Wilson CB, Uchiyama M, Kihara I. / Crucial role of CD8-positive lymphocytes in glomerular expression of ICAM-1 and cytokines in crescentic glomerulonephritis of WKY rats. / J Immunol / 158 / 4978 / 4983 / 1997 /

Fujinaka H, Yamamoto T, Takeya M, Feng L, Kawasaki K, Yaoita E, Kondo D, Wilson CB, Uchiyama M, Kihara I. / Suppression of anti-glomerular basement membrane nephritis by administration of anti-monocyte chemoattractant protein-1 antibody in WKY rats. / J Am Soc Nephrol / 8 / 1174 / 1178 / 1997 /

Hashimoto N, Kawasaki T, Kikuchi T, Uchiyama M. / Criteria of normal blood pressure and hypertension in Japanese preschool children. / J Hum Hypertens / 11 / 351 / 354 / 1997 /

Naganuma Y, Konishi T, Hongou K, Okada T, Tohyama J, Uchiyama M. / Event-related potentials (P300) and EEG activity in childhood partial epilepsy. / Brain Dev / 19 / 117 / 121 / 1997 /

Hashimoto N, Uchiyama M. / Blood pressure in pregnancy and fetal growth. / Lancet / 349 / 803 / / 1997 /

Kobayashi T, Kuraoka I, Saijo M, Nakatsu Y, Tanaka A, Someda Y, Fukuro S, Tanaka K. / Mutations in the XPD gene leading to xeroderma pigmentosum symptoms. / Hum Mutat / 9 / 322 / 331 / 1997 /

Torigoe K, Numata O, Matsunaga M, Tanaka Y, Imai C, Yamazaki H. / Effect of weight loss on body fat distribution in obese children. / Acta Paediatr Jap / 39 / 28 / 33 / 1997 /

Tohyama J, Tsunoda H, Sakuragawa N. / Characterization of human amniotic epithelial cells transformed with origin-defective SV40 T-antigen gene. / Tohoku J Exp Med / 182 / 75 / 82 / 1997 /

Ikeda K, Tohyama J, Tsujino S, Sato K, Oono T, Arata J, Endo F, Sakuragawa N. / Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer. / Jap J Hum Genet / 42 / 401 / 408 / 1997 /

Sakuragawa N, Misawa H, Ohsugi K, Kakishita K, Ishii T, Thangavel R, Tohyama J, Elwan M, Yokoyama Y, Okuda O, Arai H, Ogino I, Sato K. / Evidence for active acetylcholine metabolism in human amniotic epithelial cells / Neurosci Lett / 232 / 53 / 56 / 1997 /

Asami T, Sasagawa F, Kyo S, Asami K, and Uchiyama M. / Incidence of febrile convulsions in children with congenital hypothyroidism. / Acta Paediatr / 87 / 623 / 626 / 1998 /

Kabuki N, Okugawa T, Hayakawa H, Tomizawa S, Kasahara T, Uchiyama M. / Influence of age at onset on the outcome of steroid-sensitive nephrotic syndrome. / Pediatr Nephrol / 12 / 467 / 470 / 1998 /

Asami T, Toyabe S, and Uchiyama M. / Effects of glutathione on aminonucleoside nephrosis in rats. / Acta Medica et Biologica / 47 / 9 / 14 / 1998 /

Kakihara T, Fukuda T, Tanaka A, Emura I, Kishi K, Asami K, and Uchiyama M. / Expression of deoxycytidine kinase (dCK) gene in leukemic cells in childhood / Leukemia Lymphoma / 31 / 405 / 9 / 1998 /

Kakihara T, Onozuka J, Hayakawa H, Tanaka A, Uchiyama M, Hara M, and Yanagihara T. / Glomerular injuries--excretion of glomerular epithelial cells - induced by chemotherapy (antineoplastic drugs) independent of tubular damage. / Am J Nephrol / 18 / 504 / 7 / 1998 /

Kikuchi T, Hashimoto N, Kawasaki T, Kataoka S, Takahashi H, and Uchiyama M. / Plasma levels of carboxy terminal propeptide of type I procollagen and pyridinoline cross-linked telopeptide of type I collagen in healthy school children. / Acta Paediatrica / 87 / 825 / 9 / 1998 /

Aikawa T, Kasahara T, and Uchiyama M. / The arginine-vasopressin secretion profile of children with primary nocturnal enuresis. / Eur Urol / 33 / 41 / 4 / 1998 /

Toyama J, Kasuya H, Higuchi S, Kondo H, Naganuma Y, and Uchiyama M. / Familial neuronal migration disorder / Am J Med Genet / 75 / 481 / 4 / 1998 /

Nishizawa K, Satokata I, Kawano Y, Uchyama M. / Screening downstream genes of a homeobox gene by differential display using knockout mouse. / Acta Medida et Biologica / 46 / 63 / 70 / 1998 /

Kobayashi T, Takeuchi S, Saijo M, Nakatsu Y, Morioka H, Otsuka E, Wakasugi M, Nikaido O, and Tanaka K. / Mutational analysis of a function of xeroderma pigmentosum group A (XPA) protein in strand-specific DNA repair. / Nucleic Acids Res / 26 / 4662 / 4668 / 1998 /

Nelson JA, Chen R, Sakurai M, Pan BFA. / Nucleoside-sensitive, organic cation transporter (OCN) in opossum kidney (OK) cells. / Toxicol Sci / 42 / 375 / / 1998 /

Chen R, Sakurai M, Pan BF, Nelson JA. / Nucleoside-senseitive and energy-dependent organic cation transport (OCT) by opossum kidney (OK) proximal tubule cells. / P Am Assoc Canc Res / 39 / 610 / / 1998 /

Chen R, Sakurai M, Pan BF, and Nelson JA. / Organic cation and nucleoside transport. / FASEB J / 12 / A425 / / 1998 /

Asami T, Ciomartan T, and Uchiyama M. / Changes in serum apolipoprotein concentrations afterL-thyroxine therapy in infants with congenital hypothyroidism. / Metabolism / 48 / 1343 / 1345 / 1999 /

Toyama J, Oya Y,Ezoe T, Vanier T, Nakayasu H, Fujita N, and Suzuki K. / Ceramide accumulation is associated with increased apoptotic cell death in cultured fibroblasts of sphingolipid activator protein-deficient mouse but not in fibroblasts of patients with Farber disease. / J Inherit Metab Dis / 22 / 649 / 662 / 1999 /

Asami T, Ciomartan T, and Uchiyama M. / Thyroxine inversely regulates serum intermediate density lipoprotein levels in children with congenital hypothyroidism. / Pediatr Int / 41 / 266 / 269 / 1999 /

Cimartan T, Asami T, and Uchiyama M. / Serum lipoprotein and apolipoprotein E in infants with congenital hypothyroidism. / Pediatr Int / l41 / 249 / 252 / 1999 /

Asami T, Cimartan T, Hayakawa H, Uchiyama M, and Tomisawa S. / Apolipoprotein E epsilon 4 alle and nephritic glomerular diseases in children. / Pediatr Nephrol / 13 / 233 / 236 / 1999 /

Asami T, Hayakawa H, Ohkawa K, and Uchiyama M. / Hypercholesterolemia and glomerular diseases in urinary screening of school children. / Pediatr Nephrol / 13 / 125 / 128 / 1999 /

Nishikage T, Seki S, Toyabe S, Abo T, Kagata Y, Iwai T, and Hiraide H. / Inhibition of concanavalin A-induced hepatic injury of mice by bacterial lipopolysaccharide via the induction of IL-6 and the subsequent reduction of IL-4 / J Hepatol / 31 / 18 / 26 / 1999 /

Sakurai M, Yamaoka S, Tanaka A, Hatanaka S. / Rat 3Y1 cell retains suppressive activity for HTLV-I TAX-mediated transformation. / Acta Medica et biologica / 47 / 139 / 146 / 1999 /

Kakihara T, TanakaA, WatanabeA, Yamamoto K, Kanto K, Kataoka S, Ogawa A, Asami K, and Uchiyama M. / Expression of multi drug resistance-related genes does not contributet risk factors in newly diagnosed childhood acute lymphoblastic leukemia. / Pediatr Int / 41 / 641 / 647 / 1999 /

Aikawa T, Kasahara T, and Uchiyama M. / Circadian variation of plasma arginine vasopressin concentration, orarginine vasopressin in enuresis. / Scand J Urol Nephrol / 202 / 47 / 49 / 1999 /

Watanabe A, Kakihara T, Kanto K, Yamamoto K, Tanaka A, Numata O, Torigoe K, Toba K, Uchiyama M. / Allogeneic transplantation of CD34+ peripheral blood progenitor cells for severe combined immunodeficiency. / Acta Medica et Biologica / 47 / 115 / 120 / 1999 /

Satokata I, Kuratani M, Blum Y, Komatsu Y, Haraguchi R, Nakamura S, Suzuki K, Kosai K, Maas R, Yamada G. / Craniofacial defects associatedwith the double knockout mutation of the mouse Goosecoid gene and the Msx1 gene. / Cell Mol Biol / 45 / 589 / 599 / 1999 /

Iwai T, Yokota S, Nakao M, Okamoto T, Taniwaki M, Onodera N, Watanabe A, Kikuta A, Tanaka A, Asami K, Sekine I, Mugishima H, Nishimura Y, Koizumi S, Horikoshi Y, Mimaya J, Ohta S, Nishikawa K, Iwai A, Shimokawa T, Nakayama M, Kawakami K, Gushiken T, Hyaku / Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. / Leukemia / 13 / 38 / 43 / 1999 /

Maru Y, Kobayashi T, Tanaka K, Shibuya M. / BCR binds to the xeroderma pigmentosum group B protein. / Biochim Biophys Res Co / 260 / 309 / 312 / 1999 /

Torigoe K, Numata O, Yazaki S, Hasegawa S, Boku N, Hiura M, Ino H, Matsunaga M. / Sympathetic skin response in diabetic children: do diabetic children have diabetic neuropathy? / Pediatr Int / 41 / 631 / 636 / 1999 /

Torigoe K, Numata O, Sato T, Imai C, Takeuchi K, Yamazaki H, Hotta H, Boku N, Yazaki S, Sudo S, Kuwabara A, Hasegawa S, Hiura M, Ino H. / Contingent negative variation in children with anorexia nervosa. / Pediatr Int / 41 / 285 / 291 / 1999 /

Imai C, Yamazaki H, Tanaka Y, Matsunaga M, Numata O, and Torigoe K. / Ratio of eosinophil cationic protein/eosinophil count as a new marker in chidren with acute asthma. / Pediatr Int / 41 / 142 / 146 / 1999 /

Chen R, Pan BF, Sakurai M, Nelson JAA. / Nucleoside-sensitive organic cation transporter in opossum kidney cells. / Am J physiol / 276 / F323 / F328 / 1999 /

Tohyama J, Vanier MT, Suzuki K, Ezoe T, Matsuda J, Suzuki K. / Paradoxycal effect of acid¦Â-galactosidase gene dosage on the phenotype of twitcher mouse (genetic galactosylceramidase deficiency). / A J Hum Genet / 65 (supple) / / 503 / 1999 /

Tohyama J, Vanier MT, Suzuki K, Matsuda J, Suzuki K. / Paradoxycal effect of acid¦Â-galactosidase gene dosage on the phenotype of twitcher mouse (genetic galactosylceramidase deficiency). / J Neurochem / 73 (supple) / S64D / / 1999 /

Satokata I, Ma L, Ohshima H, Bei M, Woo I, Nishizawa K, Maeda T, Takano Y, Uchiyama M, Heaney S, Peters H, Tang Z, Maxson R, and Maas R. / MSX-2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. / Nat Genet / 24 / 391 / 395 / 2000 /

Asami T, Wada M, and Uchiyama M. / Plasma cholesteryl ester transfer protein activity is high in infants and is not affected by thyroid hormones. / Metabolism / 49 / 1176 / 1179 / 2000 /

Asami T and Uchiyama M. / Elevated serum creatinine levels in infants with congenital hypothyroidism: reflection of decreased renal function? / Acta Paediatr / 89 / 1431 / 1434 / 2000 /

Asami T, Ciomarten T, and Uchiyama M. / Relationship between serum leptin and thyroid hormones in children. / Pediatr Int / 42 / 293 / 295 / 2000 /

Kawamura T, Miyaji C, Toyabe S, Fukuda M, Watanabe H, Abo T. / Suppressive effect of antiulcer agents on granulocytes-a role for granulocytes in gastric ulcer formation. / Digest Dis Sci / 45 / 1786 / 1791 / 2000 /

Ikezumi Y, Kawachi H, Toyabe S, Uchiyama M, and Shimizu F. / An anti-CD5 monoclonal antibody ameliorates proteinuria and glomerular lesions in rat mesangioproliferative glomerulonephritis. / Kidney Int / 58 / 100 / 114 / 2000 /

Kikuchi T, Hashimoto N, Kawasaki T, and Uchiyama M. / Association of serum low-density lipoprotein metabolism with oestrogen receptor gene polymorphisms in healthy children. / Acta Paediatr / 89 / 42 / 45 / 2000 /

Torigoe K, Hasegawa S, Numata O, Yazaki S, Matsunaga M, Boku N, Hiura M, Ino H. / Influence of emission from rice straw burning on bronchial asthma in children. / Pediatr Int / 42 / 143 / 150 / 2000 /

Kikuchi T, Hashimoto N, Kawasaki T, Uchiyama M. / Association of serum low-density lipoprotein metabolism with estrogen receptor gene polymorphisms in healthy children. / Acta Peadiatr / 89 / 42 / 45 / 2000 /

Ohuchi H, Suzuki H, Toyohara k, Tatumi K, Ono Y, Arakaki Y, Echigo S. / Abnormal cardiac autonomic nervous activity after right ventricular outflow tract reconstruction. / Circulation / 28 / 2732 / 2738 / 2000 /

Ohuchi H, Yasuda K, Suzuki H, Arakaki Y, Yagihara T, Echigo S. / Ventilatory response to exercise in patients with major aortopulmonary collateral arteries after definitive surgery. / Am J Cardiol / 15 / 1223 / 1229 / 2000 /

Ohuchi H, Suzuki H, Yasuda K, Arakaki Y, Echigo S, Kamiya T. / Heart rate recovery after exercise and cardiac autonomic nervous activity in children. / Pediatr Res / 47 / 329 / 335 / 2000 /

Kikuchi T, Hashimoto N, Kawasaki T, OkugawaT, Uchiyama M. / Association between a polymorphism in the ¦Â3-adrenergic receptor gene and childhood obesity. / Acta Medica et Biologica / 48 / 135 / 139 / 2000 /

Tohyama J, Vanier MT, Suzuki K, Ezoe T, Matsuda J, Suzuki K. / Paradoxical influence of acid¦Â-galactosidase gene dosage on phenotype of the twitcher mouse (genetic galactosylceramidase deficiency). / Hum Mol Genet / 9 / 1699 / 1707 / 2000 /

Ezoe T, Vanier MT, Oya Y, Popko B, Tohyama J, Matsuda J, Suzuki K, Suzuki K. / Biochemistry and neuropathology of mice doubly deficient in synthesis and degradation of galactosylceramide. / J Neurosc Res / 59 / 170 / 178 / 2000 /

Ezoe T, Vanier MT, Oya Y, Popko B, Tohyama J, Matsuda J, Suzuki K, Suzuki K. / Twitcher mice with only a single active galactosylceramide synthase gene exhibit clearly detectable but therapeutically minor phenotypic improvements. / J Neurosc Res / 59 / 179 / 187 / 2000 /

Asami T, Wada M, and Uchiyama M. / Plasma free fatty acids in neonates with congenital hypothyroidism. / Thyroid / 11 / 81 / 84 / 2001 /

Toyabe S, Harada W, and Uchiyama M. / Oligoclonally expanding gamma delta T lymphocytes induce IgA switching in IgA nephropathy. / Clin Exp Immunol / 124 / 110 / 117 / 2001 /

Toyabe S, Watanabe A, Harada W, Karasawa T, and Uchiyama M. / Specific immunoglobulin E responses in ZAP-70-deficient patients are mediated by Syk-dependent T-cell receptor signaling . / Immunology / 103 / 164 / 171 / 2001 /

Shirane S, Sasaki M, Kogure D, Matsuda H, Hashimoto T. / Increased ictal perfusion of the thalamus in paroxysmal kinesigenic dyskinesia. / J Neurol Neurosur PS / 71 / 0 / 3 / 2001 /

Kasahara T, Hayakawa H, Okubo S, Okugawa T, Kabuki N, Tomizawa S, Uchiyama M. / Prognosis of acute poststreptococcal glomerulonephritis (APSGN) is excellent in children, when adequately diagnosed. / Pediatr Int / 43 / 364 / 367 / 2001 /

Asami T, Suzuki H, Yazaki S, Sato S, Uchiyama M. / Effects of thyroid hormone deficiency on electrocardiogram findings of congenitally hypothyroid neonates. / Thyroid / 11 / 765 / 768 / 2001 /

Matsuda J, Vanier MT, Saito Y, Tohyama J, Suzuki K, Suzuki K. / A mutation in the saposin A domein of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse. / Hum Mol Genet / 10 / 1191 / 1199 / 2001 /

Tohyama J, Matsuda J, Suzuki K. / Psychosine is as potent an inducer of cell death as C6-ceramide in cultured fibroblasts and in MOCH-1 cells. / Neurochem Res / 26 / 667 / 671 / 2001 /

Torigoe K, Numata O, Ogawa Y, Kaneko U, Usuda T, Imamura M, Takeuchi K, Suzuki H, Endo H. / Congenital negative variation in children with orthostatic dysregulation. / Pediatr Int / 43 / 469 / 477 / 2001 /

Nakamura A, Tsurusawa M, Kato A, Taga T, Hatae Y, Miyake M, Mimaya J, Nnodera N, Watanabe A, Watanabe T, Kanegane H, Matsushita T, Iwai A, Hyakuna N, Gushi K, Kawakami T, Sekine I, Izishi O, Asami K, Kikuta A, Tanaka A, Fujimoto T. / Prognostic impact of CD45 antigen expression in high-risk, childhood B-cell precursor acute lymphoblastic leukemia. / Leukemia Lymphoma / 42 / 393 / 398 / 2001 /

Watanabe T, Kawachi H, Ikezumi Y, Yanagihara T, Oda Y, and Shimizu F. / Glomerular CD8+ cells predict progression of childhood IgA nephropathy. / Pediatr Nephrol / 16 / 561 / 567 / 2001 /

Morioka Y, Koike H, Ikezumi Y, Ito Y, Oyanagi A, Gejyo F, Shimizu F, and Kawachi H. / Podocyte injuries exacerbate mesangial proliferative glomerulonephritis. / Kidney Int / 60 / 2192 / 2204 / 2001 /

Watanabe A, Kakihara T, Hara M, Tanaka A, Kanno K, Imai C, Ikarashi Y, Okubo S, Yanagihara T, Uchiyama M. / Morphological differences between glomerular epithelial cells (GEC) excreted during chemotherapy with antineoplastic drugs and GEC excreted in renal diseases. / Pediatr Int / 43 / 587 / 591 / 2001 /

Asami T, Ciomarten T, Itoh S, Uchiyama M. / Relation of apolipoprotein E polymorphism to serum lipid profiles in obese children. / Acta Medica et Biologica / 49 / 89 / 94 / 2001 /

Yamamoto, K., Ohta, S., Ito, E., Hayashi, Y., Asami, T., Mabuchi, O., Higashigawa, M., Tanimura, M. / Marginal decrease in mortality and marked increase in incidence asa result of neuroblastoma screening at 6 months of age: cohort study in seven prefectures in Japan / J Cli Oncol / 20 / 1209 / 1214 / 2002 /

Ikezumi, Y., Kanno, K., Koike, H., Tomita, M., Uchiyama, M., Shimizu, F., Kawachi, H. / FK506 ameliorates proteinuria and glomerular lesions induced by anti-Thy 1.1 monoclonal antibody 1-22-3 / Kidney Int / 61 / 1339 / 1350 / 2002 /

Endoh, K., Hirata, A., Iwai, K., Sakurai, M., Fukushi, M., Oie, M., Higuchi, M., Hall, WW., Gejyo, F., Fujii, M. / Human T-cell leukemia virus type2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax / J Virol / 76 / 2648 / 2653 / 2002 /

Kobayashi, T., Uchiyama, M., Fukuro, S., Tanaka, K. / Mutations in the XPD gene in xeroderma pigmentosum group D cell strains: confirmation of genotype-phenotype correlation / Am J Med Genet / 110 / 248 / 252 / 2002 /

Ito, Y., Kawachi, H., Morioka, Y., Nakatsue, T., Koike, H., Ikezumi, Y., Oyanagi, A., Natori, Y., Natori, Yu., Nakamura, T., Gejyo, F., Shimizu, F. / Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis / Kidney Int / 61 / 2044 / 2057 / 2002 /

Harada, W., Toyabe, S., Uchiyama, M. / Anti-endothelial IgE antibodies in children with bronchial asthma / Allergol Int / 51 / 113 / 119 / 2002 /

Hiura, M., Kikuchi, T., Kameda, K., Yamazaki, H., Nishima, M., Uchiyama, M. / The relationship between birth weight and serum insulin in obese children / Clin Pediatr Endoclinol / 11 / 43 / 48 / 2002 /

Farquhar, D., Pan, F., Sakurai, M., Ghosh, A., Mullen, CA., Nelson, JA. / Suicide gene therapy using E. coli beta-galactosidase / Cancer Chemoth Pharm / 50 / 65 / 70 / 2002 /

Asami, T., Soichiro, O., Kasahara, T., Uchiyama, M. / Asymptomatic primary hyper- N-acetyl-beta-D-glucosaminidaseuria: a new clinical entity? / Pediatr Nephrol / 17 / 560 / 565 / 2002 /

Asami, T., Uchiyama, M. / Treatment of children with familial hypercholesterolemia with colestilan, a newly developed bile acid-binding resin / Atherosclerosis / 164 / 381 / 382 / 2002 /

Sato, T., Takahashi, N., Komatsu, Y., Wada, M., Matsunaga, M., Ito, K., Uchiyama, M., Nishida, H. / Urinary acidification in extremely low birth weight infants / Early Hum Dev / 70 / 15 / 24 / 2002 /

Ishikawa, N. / Natural progress of blood glucose in full-term low-grade low-birthweight infants / Pediatr Int / 44 / 583 / 589 / 2002 /

Saito, R., Suzuki, H., Oshitani, H., Sakai, T., Seki, N., Tanabe, N. / The effectiveness of influenza vaccine against influenza A (H3N2) virus infections in nursing homes in Niigata, Japan, during the 1988-1999 and 1999-2000 seasons / Infect Cont Hosp Ep / 23 / 82 / 86 / 2002 /

Suzuki, H., Sakai, T., Saito, R., Seki, N. / Measles elimination in southern Africa / Lancet / 360 / 717 / 717 / 2002 /

Hiura, M., Torigoe, K., Numata, O., Yazaki, S., Kuwabara, A., Matsunaga, M., Hasegawa, S., Boku, N., Ino, H., Indo, Y., Miura, Y. / Case of congenital indifference to pain with anhidrosis using sympathetic skin response as a useful supportive diagnostic method in the early stage of infancy / Pediatr Int / 44 / 436 / 439 / 2002 /

Imai, C., Kakihara, T., Watanabe, A., Ikarashi, Y., Hotta, H., Tanaka, A., Uchiyama, M. / Acute suppurative thyroiditis as a rare complication of aggressive chemotherapy in children with acute myelogeneous leukemia. / Pediatr Hemat Oncol / 19 / 247 / 253 / 2002 /

Kakihara, T., Watanabe, A., Imai, C., Hotta, H., Tanaka, A., Uchiyama, M. / Chemotherapy-induced multiple vertebral compression fractures in a boy with acute lymphoblastic leukemia. / Pediatr Int / 44 / 683 / 685 / 2002 /

Toyabe, S., Harada, W., Suzuki, H., Hirokawa, T., Uchiyama, M. / Case report: Large Vessel Arteritis Associated with Human Herpesvirus 6 Infections / Clin Rheumatol / 21 / 528 / 532 / 2002 /

Kakihara, T., Imai, C., Hotta, H., Ikarashi, Y., Tanaka, A., Uchiyama, M. / Centrofacial malignant T-cell lymphoma exhibiting recurrent Fever and skin ulcer in a 3-year-old girl / Pediatr Hemat Oncol / 19 / 575 / 580 / 2002 /

Ikezumi. Y, Hurst. LA, Masaki. T, Atkins. RC, Nikolic. -Paterson DJ. / Adoptie transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation. / Kidney International / 63 / 83 / 95 / 2003 /

Kakihara. T, Imai. C, Hotta. H, Ikarashi. Y, Tanaka. A, Uchiyama. M. / Impaired tubular excretory function as a late renal side effect of chemotherapy in children. / Journal of Pediatric Hematology and Oncology / 25 / 209 / 214 / 2003 /

Ikezumi. Y, Atkins. RC, Nikolic. -Paterson DJ. / Interferon-gamma Auguments Acute Macrophage-Mediated Renal Injury Via a Glucocorticoid-Sensitive Mechanism. / Journal of American Society of Nephrology / 14 / 888 / 898 / 2003 /

Masaki. T, Foti. R, Hill. PA, Ikezumi. Y, Atkins. RC, Nikolic-Paterson DJ. / Activation of the ERK pathway precedes tubular proliferation in the obstructed rat kidney. / Kidney International / 63 / 1256 / 1264 / 2003 /

Imai. C, Kakihara. T, Iwabuchi. H, Tanaka. A, Furukawa. T, Uchiyama. M. / Glomerular vasculopathy after unrelated cord blood transplantation. / Pediatric Nephrology / 18 / 399 / 402 / 2003 /

Nishina. M, Kikuchi. T, Yamazaki. H, Kameda. K, Hiura. M, Uchiyama. M. / Relationship among systolic blood pressure,serum insulin and leptin, and visceral fat accmulation in obese children. / Hypertension Research / 26 / 281 / 288 / 2003 /

Hiura. M, Kikuchi. T, Nagasaki. K, Uchiyama. M. / Elevation of serum C-reactive protein levels is associated with obesity in boys. / Hypertension Research / 26 / 541 / 546 / 2003 /

Kakihara. T, Imai. C, Kaneko. T,Tanaka. A, Uchiyama.M. / Atypical hemophagocytic lymphohistiocytosis following bacterial tonsillitis in acute lymphoblastic leukemia. / Leuk Lymphoma / 44 / 1247 / 1248 / 2003 /

Kakihara. T, Tanaka. A, Imai .C, Ikarashi.Y, Uchiyama. M. / Emura I. Psychosomatic reaction exhibiting hemorrhagic erythema and motorsensory disturbance. / Pediatr Int / 45 / 472 / 474 / 2003 /

Toyabe S, Harada W, Uchiyama M. / Biclonal expansion of T cells infected with monoclonal Epstein-Barr virus (EBV) in a patient with chronic, active EBV infection. / Clin Exp Immunol / 134 / 92 / 97 / 2003 /

Watanabe H, Weerasinghe A, Miyaji C, Sekikawa H, Toyabe S, Mannor MK, Morshed SR, Halder RC, Kobayashi J, Toma H, Sato Y, Iwai K, Matsuoka H, Abo T. / Expansion of unconventional T cells with natural killer markers in malaria patients. / Parasitol Int / 52 / 61 / 70 / 2003 /

Jose MD, Ikezumi Y, Van Rooijen N, Atkins RC, Chadban SJ. / Macrophages act as effectors of tissue damage in acute renal allograft rejection. / Transplantation / 76 / 1015 / 1022 / 2003 /

Kobayashi T, Uchiyama M. / Characterization of assembly of recombinant type IV collagen ¦Á3, ¦Á4, and ¦Á5 chains in transfected cell strains. / Kidney International / 64 / 1986 / 1996 / 2003 /

Kanno K, Kawachi H, Uchida Y, Hara M, Shimizu F, Uchiyama M. / Urinary sediment podocalyxin in children with glomerular diseases. / Nephron Clinical Practice / 95 / c91 / c99 / 2003 /

Yamazaki H, Torigoe K, Numata O, Nagai S, Haniu H, Uchiyama A, Ogawa Y, Imamura M, Hasegawa S. / Neonatal clinical outcome after elective caesarean section before the onset of labor at the 37th and 38th week of gestation. / Pediatrics International / 45 / 379 / 382 / 2003 /

Yamazaki H, Ito S, Yoshida H. / Acanthosis nigricans is a reliable cutaneous marker of insulin resistance in obese Japanese children. / Pediatrics International / 45 / 701 / 705 / 2003 /

Kameda K, Kikuchi T, Yamazaki H, Hiura M, Uchiyama M. / The relationship of serum levels of Malondialdehyde-modified low density lipoprotein to serum lipid and anthrometric measurements in shcool children. / Acta Medica et Biologica / 51 / 67 / 73 / 2003 /

Ishikawa N, Saou Nm, Uchiyama M, Katsumata N, Tanaka T. / Serum levels of 20-kilodalton human growth hormone in children with simple obesity. / Clin Pediatr Endocrinol / 12 / 49 / 56 / 2003 /

Ishikawa N, Tanaka T, Hashimoto K, Wada M. / A Case of Turner Syndrome with Congenital Hypothyroidism Untreated until Age 38 Years. / Hormone Research / 59 / 50 / 54 / 2003 /

Toyabe S, Harada W, Uchiyama M. / Interleukin-3-producing CD4+ T-cells support eosinophil survival in a patient with transient hypereosinophilia. / European Journal of Pediatrics / 162 / 889 / 890 / 2003 /

Iwabuchi H, Kakihara T, Tanaka A, Uchiyama M, Shibuya H, Umezu H. / Congenital Rosai-Dorfman disease without lymphadenopathy. / Pediatric Pathology & Molecular Medicine / 22 / 399 / 403 / 2003 /

Asami T and Uchiyama M. / Sodium handling in congenitally hypothyroid neonates / Acta Paediatr / 93 / 22 / 24 / 2004 /

Asami T, Tomizawa S and Uchiyama M. / Effect of oral camostat mesilate on hematuria and/or proteinuria in children. / Pediatr Nephrol / 19 / 313 / 316 / 2004 /

Ohashi M, Sakurai M, Higuchi M, Mori N, Fukushi M, Oie M, Uchiyama M, Hatanaka M and Fujii M. / Human T-cell leukemia virus type 1 Tax oncoprotein induces and interacts with a multi-PDZ domain protein, MAGI-3. / Virology / 320 / 52 / 62 / 2004 /

Nagasaki K, Kikuchi T, Hiura M and Uchiyama M. / Obese Japanese children habe low bone density after puberty. / J Bone Miner Metab / 22 / 376 / 381 / 2004 /

Imai C, Mihara K, Andreansky M, Nicolson IC, Pui CH, Geiger TL and Campana D. / Chimeric receptors with 4-1 BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. / Leukemia / 18 / 676 / 684 / 2004 /

Imai C, Ross ME, Reid G, Coustan-Smith E, Schultz KR, Pui CH, Downing JR and Campana D. / Expression of the adaptor protein BLNK/SLP-65 in childhood acute lymphoblastic leukemia. / Leukemia / 18 / 922 / 925 / 2004 /

Ikezumi Y, Hurst L, Atkins RC, Nikolic-Paterson DJ. / Macrophage-mediated renal injury is dependent on signaling via the JNK pathway. / J Am Soc Nephrol / 15 / 1775 / 1784 / 2004 /

Wada M. / Measurement of hepatic phenylalanine metabolism in children using the [13C]-phenylalanine breath test and gas chromatography-mass spectrometry. / Journal of Chromatography B / 806 / 5 / 10 / 2004 /

Ikezumi Y, Kanno K, Karasawa T, Han GD, Ito Y, Koike H, Toyabe S, Uchiyama M, Shimizu F and Kawachi H. / The role of lymphocytes in the experimental progressive glomerulonephritis. / Kidney Int / 66 / 1036 / 1048 / 2004 /

Oishi T, Iwata S, Nonoyama M, Tsuji A and Sunakawa K / Double-blind comparative study on the care of the neonatal umbilical cord using 80% ethanol with or without chlorhexidine. / Journal of Hospital Infection / 58 / 34 / 37 / 2004 /

Sakai T, Suzuki H, Sasaki A, Saito R, Tanabe N and Taniguchi K. / Geographic and temporal trends in influenzalike illness, Japan, 1992-1999. / Emerging infectious diseases / 10 / 1822 / 1826 / 2004 /

Tsuchida M, Nagura T, Bai XF, Li CC, Tomiyama-Miyaji C, Kawamura T, Uchiyama M and Abo T. / Granulocytic activation and reciprocal immunosuppression induced by dehydration: relationship with rena failure. / Biomedical Research / 25 / 171 / 178 / 2004 /

Ikarashi Y, Kakihara T, Imai C, Tanaka A, Watanabe A and Uchiyama M. / Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children. / Pediatrics International / 46 / 570 / 575 / 2004 /

Ogawa Y, Hiura M, Kikuchi T, Nagasaki K, Iwata Y and Uchiyama M. / The levels of serum low-density lipoprotein cholesterol using direct measurement in healthy Japanese school children. / Clin Pediatr Endocrinol / 13 / 55 / 58 / 2004 /

Imamura M, Kakihara T, Kobayashi T, Imai C, Tanaka A and Uchiyama M. / Anticancer drugs overexpress Fas-associated phosphatase-1 in some leukemic cells. / Acta Medica et Biologica / 52 / 81 / 89 / 2004 /

Toyabe S, Kaneko U and Uchiyama M. / Decreased DAP12 expression in natural killer lymphocytes from patients with systemic lupus erythematosus is associated with increased transcript mutations. / Journal of Autoimmunity / 23 / 371 / 378 / 2004 /

Ikarashi Y, Kakihara T, Imai C, Tanaka A, Watanabe A and Uchiyama M. / Double leukemias simultaneously showing lymphoblastic leukemia of the bone marrow and monocytic leukemia of the central nervous system. / American Journal of Hematology / 75 / 164 / 167 / 2004 /

Yamazaki H, Torigoe K, Numata O, Haniu H, Uchiyama A, Ogawa Y, Kaneko U, Imamura M and Hasegawa S. / Mitochondrial trifunctional protein deficiency in a lethal neonate. / Pediatr Int / 46 / 178 / 180 / 2004 /

Nagasaki K, Horikawa R, Fujisawa K, Hata I, Shigematsu Y and Tanaka T. / A case of female pseudohermaphroditism caused by aromatase deficiency. / Clinical Pediatric endocrinology / 13 / 59 / 64 / 2004 /

Nagasaki K, Horikawa R, Nagaishi J, Honnna T, Sekiguchi A, Tsunematsu Y and Tanaka T. / Virilizing adrenocortical carcinoma invading the right atrium with histological high-grade malignancy and p53 mutation in a 3-year-old child: identification of post operative adjuvant chemothrapy. / Clinical Pediatric endocrinology / 13 / 25 / 32 / 2004 /

Ogawa Y, Kikuchi T, Nagasaki K, Hiura M, Tanaka Y and Uchiyama M. / Usefulness of serum adiponectin level as a diagnostic marker of metabolic syndrome in obese Japanese children. / Hypertens Res / 28 / 51 / 57 / 2005 /

Toyabe S, Nakamizo M, Uchiyama M and Akazawa K. / Circannual variation in the onset and relapse of steroid-sensitive nephrotic syndrome. / Pediatr Nephrol / 20 / 470 / 473 / 2005 /

Ikarashi K, Li B, Suwa M, Kawamura K, Morioka T, Yao J, Khan F, Uchiyama M and Oite T. / Bone marrow cells contribute to regeneration of damaged glomerular endothelial cells. / Kidney Int / 67 / 1925 / 1933 / 2005 /

Nagasaki K, Shimomura Y, Suyama T, Magara S, Ogawa Y, Hiura M, Kikuchi T and Uchiyama M. / Two cases of pseudohypoparathyroidism type Ia in duozygotic twins with different phenotypes. / Clin Pediatr Endocrinol / 14 / 39 / 44 / 2005 /

Toyabe S, Kaneko U, Hara M and Uchiyama M. / Expression of immunoglobulin E-dependent histamine-releasing factor in idiopathic nephrotic syndrome of childhood. / Clin Exp Immunol / 142 / 162 / 166 / 2005 /

Tanaka Y, Kikuchi T, Nagasaki K, Hiura M, Ogawa Y and Kikuchi T. / Lower birth weight and visceral fat accumulation are related to hyperinsulinemia and insulin resistance in obese Japanese children. / Hypertens Res / 28 / 529 / 536 / 2005 /

Ikezumi Y, Suzuki T, Hayafuji S, Okubo S, Nikolic-Paterson DJ, Kawachi H, Shimizu F and Uchiyama M. / The sialoadhesin (CD169) expressing a macrophage subset in human proliferative glomerulonephritis. / Nephrol Dial Transpl / 20 / 2704 / 2713 / 2005 /

Suzuki H, Silverman ED, Wu X, Borges C, Zhao S, Isacovics B and Hamilton RM / Effect of maternal autoantibodies on fetal cardiac conduction: an experimental murine model. / Pediatr Res / 57 / 557 / 562 / 2005 /

Suzuki H,Ohuchi H,Hiraumi Y,Yasuda K ,Echigo S. / Effects of postural change on oxygen saturation and respiration in patients after the Fontan operation : Platypnea and orthodeoxia. / International Journal of Cardiology / 106 / 211 / 217 / 2006 /

Toyabe S,Cao P,Abe T,Uchiyama M,Akazawa K. / Impact of sociocultural factors on hospital length of stay in children with nephrotic syndrome in Japan. / Health Policy / 76 / 259 / 265 / 2006 /

Otsuka T,Fujinaka H,Kamimura T,Tanaka Y,Hayakawa H,Sato M,Syoubugawa Y,Saito R,Tomizawa S,Suzuki H. / Influenza vaccination in severely multiply handicapped persons/children. / Vaccine / 24 / 4096 / 4101 / 2006 /

Taneike I,Otsuka T,Dohmae S,Saito K,Ozaki K,Takano M,Higuchi W,Takano T,Yamamoto T. / Molecular nature of methicillin-resistant Staphylococcus aureus derived from explosive nosocomial outbreaks of the 1980s in Japan. / FEBS Lett / 580 / 2323 / 2334 / 2006 /

Kamimura T,Tohyama J,Oishi M,Akasaka N,Kanazawa O,Sasagawa M,Kato M,Ohno K,Masuda H,Kameyama S,Uchiyama M. / Magnetoencephalography in Patients with Tuberous Sclerosis and Localization-related Epilepsy. / Epilepsia / 47 / 991 / 997 / 2006 /

Yamada K,Matsuzawa H,Uchiyama M,Ingrid L..Kwee,Nakada T. / Brain Developmental Abnormalities in Prader-willi Syndrome Detected by Diffusion Tensor Imaging. / PEDIATRICS / 118 / e442 / e448 / 2006 /

Peter M. Rabinovich,Marina E.. Komarovskaya, Zhi-jia Ye,Chihaya Imai,Dario Campana, Erkut Bahceci, Sherman M. Weissman. / Synthetic Messenger RNA as a Tool for Gene Therapy. / HUMAN GENE THERAPY / 17 / 1027 / 1035 / 2006 /

Ikezumi Y,Suzuki T,Imai N,Ueno M,Narita I,Kawachi H,Shimizu F,Nikolic-Paterson DJ,Uchiyama M. / Histological differences in new-onset IgA nephropathy between children and adults. / Nephrol Dial Transplant / 21 / 3466 / 3474 / 2006 /

Otsuka T,Saito K,Dohmae S,Takano T,Higuchi W,Takizawa Y,Okubo T,Iwakura N,Yamamoto T. / Key adhesin gene in community-acquired methicillin-resistant Staphylococcus aureus. / Biochemical and Biophysical Research Communications / 346 / 1234 / 1244 / 2006 /

Yamamoto T,Dohmae S,Saito K,Otsuka T,Takano T,Chiba M,Fujikawa K,Tanaka M. / In Vitro Activity of DX-619, a Novel Des-F(6)-Quinolone, against Panton-Valentine Leucocidin-Positive Methicillin-Resistant Staphylococcus aureus from the Community and Hospitals. / Anyimicrobial Agents and Chemotherapy / 50 / 4077 / 4086 / 2006 /

Kaneko U,Toyabe S,Hara M,Uchiyama M. / Increased mutations of CD72 transcript in B-lymphocytes from adolescent patients with systemic lupus erythematosus. / Pediaatric allergy and immunology / 17 / 565 / 571 / 2006 /

Kure S,Kato K,Dinopoulos A,Gail C,DeGrauw TJ,Christodoulou J,Bzduch V,Kalmanchey R,Fekete G,Trojovsky A,Plecko B,Breningstall G,Tohyama J,Aoki Y,Matsubara Y. / Comprehensive mutation analysis of GLDC, AMT ,and GCSH in nonketotic hyperglycinemia. / Hum Mutat / 27 / 343 / 352 / 2006 /

Oishi M,Kameyama S,Masuda H,Tohyama J,Kanazawa O,Sasagawa M,Otsubo H. / Single and multiple clusters of magnetoencephalographic dipoles in neocortical epilepsy : significance in characterizing the epileptogenic zone. / Epilepsia / 47 / 355 / 364 / 2006 /

Tanaka T,Jiang S,Hotta H,Takano K,Iwanari H,Sumi K,Daigo K,Ohashi R,Sugai M,Ikegami C,Umezu H,Hirayama Y,Midorikawa Y,Hippo Y,Watanabe A,Uchiyama Y,Hasegawa G,Reid P,Aburatani H,Hamakubo T,Sakai J,Naito M,Kodama T. / Dysregulated expression of P1 and P2 promoter-driven hepatocyte unclear factor-4alpha in the pathogenesis of human cancer. / J Pathol / 208 / 662 / 672 / 2006 /

Ikezumi Y, Kabuki N, Hayakawa H, Matsui T, Gunji T, Uchiyama M. / Two patients with arthrogryposis-renal tubular dysfunction-cholestasis syndrome in a Japanese family. / Pediatrics International / 48 / 416 / 419 / 2006 /

Fujimoto A,Tohyama J,Homma J,Masuda H,Oishi M,Kameyama S. / Auditory evoked magnetic field study of two cases of congenital perisylvian syndrome. / Nervous system in Children / 31 / 447 / 448 / 2006 /

Nagasaki K,Asami T,Kikuchi T,Uchiyama M. / Longitudinal Growth of the Short Bones of the Hand in a Girl with Pseudohypoparathyroidism Type Ia. / Clin Pediatr Endocrinol / 16 / 23 / 29 / 2007 /

Nagasaki K,Kikuchi T,Uchiyama M. / Different Skeletal Phenotypes in a Mother and Two Daughters with Short Stature Homeobox-Containing Haploinsufficiency. / Clin Pediatr Endocrinol / 16 / 69 / 74 / 2007 /

Suzuki T,Ikezumi Y,Okubo S,Uchiyama M,Takahashi K,Shiraga H,Hattori M. / Epstein-Barr virus DNA load and seroconversion in pediatric renal transplantation with tacrolimus immunosuppression . / Pediatr Trasplant / 11 / 749 / 754 / 2007 /

Wada M,Wada Y,Kajiwara M,Takatori K,Uchiyama M. / Evaluation of liver fibrosis in post operative biliary atresia patients using the 13C-phenylalanine breath test. / Pediatr International / 49 / 836 / 841 / 2007 /

Otsuka T,Zaraket H,Takano T,Saito K,Dohmae S,Higuchi W,Yamamoto T. / Macrolide-lincosamide-streptogramin B resistance phenotypes and genotypes among staphylococcus aureus clinical isolates in Japan. / Clinical Microbiology and Infection / 13 / 325 / 327 / 2007 /

Zaraket H,Otsuka T,Saito K,Dohmae S,Takano T,Higuchi W,Ozaki K,Takano M,Reva I,Baranovich T,Yamamoto T. / Molecular Characterization of Methicillin-Resistant Staphylococcus aureus in Hospitals in Niigata , Japan : Divergence and Transmission. / Microbiology and Immunology / 51 / 171 / 176 / 2007 /

Ogawa Y,Uchigata Y,Otani T,Iwamoto Y. / Proportion of Diabetes Type in Early-Onset Diabetes in Japan. / DIABETES CARE / 30 / e30 / / 2007 /

Sasaki (Uchiyama) A,Suzuki H,Sakai T,Sato M,Shobugawa Y,Saito R. / Measles outbreaks in high schools closely associated with sporting event in Niigata , Japan. / J Infect / 55 / 179 / 183 / 2007 /

Marin V,Kakuda H,Dander E,Imai C,Campana D,Biondi A,D'Amico G. / Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-¦Æ activating signal. / Experimental Hematology / 35 / 1388 / 1397 / 2007 /

Otsuka T,Fujinaka H,Katsuyama K,Iizawa M,Kinoshita S,Tanaka Y,Saito R,Suzuki H,Tomizawa S. / Influenza vaccination for severely multiply handicapped persons/children in the 2005-2006 season. / Vaccine / 25 / 4521 / 4524 / 2007 /

Suzuki T,Ikezumi Y,Okubo S,Uchiyama M,Takahashi K,Shiraga H,Hattori M. / Epstein-Barr virus DNA load and seroconversion in pediatric renal transplantation with tacrolimus immunosuppression . / Pediatr Trasplant / 11 / 749 / 754 / 2007 /

Abe Y,Kikuchi T,Nagasaki K,Hiura M,Tanaka Y,Ogawa Y,Uchiyama M. / Lower Birth Weight Associated with Current Overweight Status Is Related with the Metabolic Syndrome in Obese Japanese Children. / Hypertens Res / 30 / 627 / 634 / 2007 /

Iwabuchi H,Kawasaki T,Yamoto T,Uchiyama M,Nakata K,Naito M. / Expression of PU.1 and terminal differentiation of alveolar macrophages in newborn rats. / Cell Tissue Res / 329 / 71 / 79 / 2007 /

Saitoh N,Kanazawa O,Tohyama J,Akasaka N,Kamimura T. / Magnetoencephalographic Findings of Panayiotopoulos Syndrome With Frontal Epileptic Discharges. / Pediatr Neurol / 36 / 190 / 194 / 2007 /

Ichiyama T,Siba P,Suarkia D,Takasu T,Miki K,Kira R,Kusuhara K,Hara T,Toyama J,Frukawa S. / Serum levels of matrix metalloproteinase -9 and tissue inhibitors of metalloproteinases 1 in subacute sclerosing panencephalitis. / J Neurol Sci / 252 / 45 / 48 / 2007 /

Guerrini R,Moro F,Kato M,Barkovich AJ,Shiihara T,McShane MA,Hurst J,Loi M,Tohyama J, Hayasaka K,Kang UJ,Dobyns WB. / Expansion of the first poly A tract of ARX causes infantile spasms and status dystonicus. / Neurology / 69 / 427 / 433 / 2007 /

Kato M,Saitoh S,Kamei A,Shiraishi H,Ueda Y,Akasaka M,Tohyama J,Akasaka N,Hayasaka K. / A longer polyalanine expansion mutation in the ARX gene causes early infantile epileptic encephalopathy with suppression-burst pattern (Ohtahara syndrome). / Am J Hum Genet / 81 / 361 / 366 / 2007 /

Wada M,Wada Y,Kajiwara M,Takatori K,Uchiyama M. / Evaluation of liver fibrosis in post operative biliary atresia patients using the 13C-phenylalanine breath test. / Pediatr International / 49 / 836 / 841 / 2007 /

Imai C,Kakuda H,Fujisaki H,Iwamoto S,Campana D. / Genetic Modification of Natural Killer Cells for Leukemia Therapies. / Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry / / 101 / 108 / 2007 /

Kikuchi T,Nagasaki K,Hiura M,Tanaka Y,Abe Y,Ogawa Y,Uchiyama M. / Developmental origins of adult health and disease : A pediatric perspective in current Japan. / 2nd Hiroshima Conference on Education and Science in Dentistry / / 61 / 64 / 2007 /

Tohyama J,Akasaka N,Saito N,Yoshimura J,Nishiyama K,Kato M. / Megalencephaly and polymicrogyria with polydactyly syndrome. / Pediatr Neurol / 37 / 148 / 151 / 2007 /

Wada M,Kusuda S,Takahashi N,Nishida H. / Fluid and electrolyte balance of extremely immature infants less than 24 weeks of gestation. / Pediatr International / 50 / 33 / 336 / 2008 /

Yoshida S,Higuchi M,Shoji T,Yoshita M,Ishioka K,Takahashi M,Oie M,Tanaka Y,Uchiyama M,Fujii M. / Knockdown of synapse-associated protein Dlg1 reduces syncytium formation induced by human T-cell leukemia virus type 1. / Virus Genes / 37 / 9 / 15 / 2008 /

Kobayashi T,Kakihara T,Uchiyama M. / Mutational analysis of type ? collagen ¦Á5 chain, with respect to heterotrimer formation. / Biochemical and Biophysical Research Communications / 366 / 60 / 65 / 2008 /

Ikezumi Y,Suzuki T,Karasawa T,Kawachi H,Nikolic-Paterson DJ,Uchiyama M / Use of mizoribine as a rescue drug for steroid-resistant pediatric IgA nephropathy. / Pediatr Nephrol / 23 / 645 / 650 / 2008 /

Ikezumi Y,Suzuki T,Karasawa T,Kawachi H,Nikolic-Paterson DJ,Uchiyama M. / Activated macrophages down-regulate podocyte nephrin and podocin expression via stress-activated protein kinases. / Biochem Biophys Res Commun / 376 / 706 / 711 / 2008 /

Ogawa Y,Uchigata Y, Iwamoto Y. / Progression factors of carotid intima-media thickness and plaque in patients with long-term,early-onset type 1 diabetes mellitus in japan:simultaneous comparison with diabetic retinopathy. / J Atheroscler thromb / 16 / 821 / 828 / 2009 /

Hasegawa H,Okubo S,Ikezumi Y,Uchiyama K,Hirokawa T,Hirano H,Uchiyama M. / Hyponatremia due to an excess of arginine vasopressin is common in children with febrile disease. / Pediatr Nephrol / 24 / 507 / 511 / 2009 /

Nagasaki K,Usui T, Asami T, Ogawa Y, Kikuchi T,Uchiyama M. / H62L Mutation of CYP21A2Identified in the Non-Classical Form of 21-Hydroxylase Deficiency. / Clin Pediatr Endocrinol / 18 / 11 / 113 / 2009 /

Nemoto T,Imai C,Kaneko U,Takachi T,Iwabuchi H,Tanaka A,Nakamura G,Ogose A,Uchiyama M. / Effect of charcoal hemoperfusion for removal of plasma methotrexate in a patient with acute renal failure. / Pediatr Hematol Oncol / 26 / 520 / 525 / 2009 /

Nagasaki K,Tsumanuma I, Yoneoka Y,Ogawa Y,Kikuchi T,Uchiyama M. / Spontaneous regression of isolated neurohypophyseal langerhans cell histiocytosis with diabetes insipidus. / Endocr J / 56 / 721 / 725 / 2009 /

Ikezumi Y,Suzuki T,Karasawa T,Hasegawa H,Kawachi H,Nikolic-Paterson DJ,Uchiyama M. / Contrasting Effects of Steroids and Mizoribine on Macrophage Activation and Glomerular Lesions in Rat Thy-1 Mesangial Proliferative Glomerulonephritis. / Am J Nephrol / 31 / 273 / 282 / 2010 /

Kobayashi T,Uchiyama M. / Mutant-type ¦Á5(IV) collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer. / Pediatric Nephrology / 25 / 1169 / 1172 / 2010 /






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